Article

Identification, Purification and Characterization of Mast Cells in Murine Liver Fibrosis: Novel Methods, Expression Signatures and Correlation with Severity

2025-07-28

Abstract excerpt

Mast cells (MCs) are myeloid cells of the innate immune system. As a first line of defense, they fulfill effector functions and immune modulatory properties. Upon activation, they release pro-inflammatory mediators such as cytokines and proteases. It has been suggested that MCs may contribute to the development of liver fibrosis. However, investigating hepatic MC biology in mice is challenging due to low MC number...

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Literature Corpus work: a567d6f2-5f51-567f-a9be-78a61251c932
DOI: 10.1101/2025.07.25.666577

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