Article
Role of mast cells in progressive renal diseases.
Journal of the American Society of Nephrology : JASN - 1 Dec 2008
Holdsworth Stephen R, Summers Shaun A
Abstract excerpt
Advances in understanding mast cell biology reveal their diverse functional capacity well beyond already established roles in host defense against parasites and allergic disease. Mast cells can initiate, amplify, and direct innate and adaptive immune responses. They also modulate inflammation and regulate immunity. Mast cells potentially induce tissue repair and direct fibrosis; however, they also play other...
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