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Article

The Dynamic Interplay Between Mast Cells, Aging/Cellular Senescence, and Liver Disease

29 Jul 2020

Abstract excerpt

Mast cells are key players in acute immune responses that are evidenced by degranulation leading to a heightened allergic response. Activation of mast cells can trigger a number of different pathways contributing to metabolic conditions and disease progression. Aging results in irreversible physiological changes affecting all organs, including the liver. The liver undergoes senescence, changes in protein...

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PMID: 32727636
DOI: 10.3727/105221620x15960509906371

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