Article
Isolation of Mature (Peritoneum-Derived) Mast Cells and Immature (Bone Marrow-Derived) Mast Cell Precursors from Mice.
PloS one - 1 Jan 2016
Meurer Steffen K, Neß Melanie, Weiskirchen Sabine, Kim Philipp, Tag Carmen G, Kauffmann Marlies, Huber Michael, Weiskirchen Ralf
Abstract excerpt
Mast cells (MCs) are a versatile cell type playing key roles in tissue morphogenesis and host defence against bacteria and parasites. Furthermore, they can enhance immunological danger signals and are implicated in inflammatory disorders like fibrosis. This granulated cell type originates from the myeloid lineage and has similarities to basophilic granulocytes, both containing large quantities of histamine and...
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