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New Insight into Intestinal Mast Cells Revealed by Single-Cell RNA Sequencing

21 May 2024

Abstract excerpt

Mast cells (MCs) are tissue-resident immune cells distributed in all tissues and strategically located close to blood and lymphatic vessels and nerves. Thanks to the expression of a wide array of receptors, MCs act as tissue sentinels, able to detect the presence of bacteria and parasites and to respond to different environmental stimuli. MCs originate from bone marrow (BM) progenitors that enter the circulation...

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PMID: 38891782
DOI: 10.3390/ijms25115594

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