Article

Characterization of human senescent cell biomarkers for clinical trials

2024-11-05

Abstract excerpt

<h4>ABSTRACT</h4> There is an increasing need for blood-based biomarkers of senescent cell burden to facilitate selection of participants for clinical trials. Potential candidates include p16 Ink4a expression in peripheral blood T-cells and circulating protein concentrations of the senescence-associated secretory phenotype (SASP). p16 Ink4a is encoded by the CDKN2A locus, which produces six variant transcripts in...

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Literature Corpus work: a55b8999-5d2d-543f-816b-ac725bb245da
DOI: 10.1101/2024.11.02.24316643

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