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Performance of cellular senescence measure, p16, and DNA methylation clocks in a clinically relevant model of age acceleration

2023-05-14

Abstract excerpt

<h4>ABSTRACT</h4> Cellular senescence and DNA methylation are primary aging mechanisms emerging as a potential means of monitoring human aging and evaluating interventions thought to either accelerate or slow an individual’s aging trajectory. However, it is largely unknown whether cellular senescence and signatures of methylation of the specific CpG islands that comprise various epigenetic clocks correlate in huma...

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Literature Corpus work
7a17ddec-cb66-55e3-bcf0-d276ed7c2a4e
DOI
10.1101/2023.05.06.23289535
Open publication

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