Article

Evaluating the Therapeutic Viability of Bacterially Expressed Human TLK1B-Kinase Domain for Cancer Drug Design

2022-02-21

Abstract excerpt

The role of protein kinases is vital in diverse cellular functions. The alterations in the expression patterns of protein kinases often implicate human cancer initiation and progression. Human Tousled-like kinases (TLKs) are evolutionary kinases found in the cell signalling pathway and are involved in DNA repair, replication and chromosomal integrity. The direct association of TLKs to cancer; amplification of both...

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Literature Corpus work: a528cd70-48bf-5bc5-9765-92d4f4d56fd3
DOI: 10.21203/rs.3.rs-1314176/v1

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