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Article

The Development of Graves' Disease and the CTLA-4 Gene on Chromosome 2q33

1999-07-01

Abstract excerpt

Case-control studies suggest that the CTLA-4 gene may be a susceptibility locus for Graves' disease. The previously reported A/G polymorphism at position 49 in exon 1 of the CTLA-4 gene was, therefore, investigated in a case-control (n = 743) and family-based (n = 179) dataset of white Caucasian subjects with Graves' disease. The relationship between CTLA-4 genotype and severity of thyroid dysfunction at diagnosis...

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Literature Corpus work
a4ca2fe8-defd-5902-a869-766f5e74be4e
DOI
10.1210/jc.84.7.2398
Open publication

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The Development of Graves' Disease and the CTLA-4 Gene on Chromosome 2q33DOI 10.1210/jc.84.7.2398
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