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Article

Meta-Analysis of CTLA-4 +49 Gene Polymorphism and Susceptibility to Graves' Disease.

Critical reviews in eukaryotic gene expression - 1 Jan 2020

Huang Fengli, He Qin, Jiao Xiaoli, Zhang Hong, Chang Qing

Abstract excerpt

Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) plays an important role in the initiation and development of Graves' disease (GD), especially CTLA-4 +49A/G polymorphism and genetic susceptibility to GD. However, the current conclusions are consistent. Therefore, this study adopted meta-analysis method to assess the exact correlation between this polymorphism and GD risk. METHODS: Literature searches were...

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PMID: 33389876
DOI: 10.1615/CritRevEukaryotGeneExpr.2020034872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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