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Article

Association of CTLA-4 +49 A/G and CT60 Gene Polymorphism with Graves' Disease.

The Egyptian journal of immunology - 1 Jun 2017

Fouad Nehad A, Saeed Aml M, Mahedy Ahmed W

Abstract excerpt

Graves' disease (GD) is an organ specific autoimmune disease of thyroid gland with genetic and environmental causes. One of genetic factors that have been implicated in the development of this disease is CTLA-4 gene polymorphism. This study aimed to investigate the association of CTLA-4 polymorphisms at position +49A/G, and CT60 with susceptibility to Graves' disease in Saudi patients. 40 adult Saudi patients...

Topics

Adult
Alleles
CTLA-4 Antigen
Case-Control Studies
Gene Frequency
Genetic Predisposition to Disease
Genotype
Graves Disease
Humans
Polymorphism, Genetic
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saudi Arabia

Source

Identifiers

PMID: 29528580

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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