Article
CTLA-4 gene polymorphism and its association with Graves' disease in the Lebanese population.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Jun 2004
Nakkash-Chmaisse H, Makki R F, Abdelhamid E, Fakhoury H, Salti N N, Salti I
Abstract excerpt
Graves' disease is an organ-specific autoimmune disease that has a female predominance. It is probably the result of a complex interaction of genetic and environmental factors. This disease is characterized by immune system activation, evidenced by elevated serum thyroid-specific autoantibodies and lymphocytic infiltration of the target organ (the thyroid gland), associated with raised levels of circulating...
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