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Article

Association of CTLA-4 gene polymorphism with Graves' disease and ophthalmopathy in Iranian patients.

European journal of internal medicine - 1 Jul 2009

Esteghamati Alireza, Khalilzadeh Omid, Mobarra Zahra, Anvari Mehdi, Tahvildari Maryam, Amiri Hoda Mojazi, Rashidi Armin, Solgi Ghasem, Parivar Kazem, Nikbin Behrouz, Amirzargar Aliakbar

Abstract excerpt

BACKGROUND: The cytotoxic T lymphocyte associated antigen-4 (CTLA-4) gene, is one of the candidate genes for susceptibility to Graves' disease. This study aimed to investigate the association of Graves' disease and Graves' ophthalmopathy with polymorphisms at position +49 in exon 1 and positions -318 and -1147 in the promoter region of CTLA-4 gene in Iranian patients. METHODS: A total of 205 unrelated Iranian...

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Share to Antigens, CD
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Promoter Regions, Genetic

Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 19524188
DOI: 10.1016/j.ejim.2008.12.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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