Article
The genetics of Graves' disease.
Reviews in endocrine & metabolic disorders - 1 Feb 2024
Grixti Lydia, Lane Laura C, Pearce Simon H
Abstract excerpt
Graves' disease (GD) is the commonest cause of hyperthyroidism and has a strong female preponderance. Everyday clinical practice suggests strong aggregation within families and twin studies demonstrate that genetic factors account for 60-80% of risk of developing GD. In this review, we collate numerous genetic studies and outline the discoveries over the years, starting with historic candidate gene studies and...
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