Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Soluble CTLA-4 receptor an immunological marker of Graves' disease and severity of ophthalmopathy is associated with CTLA-4 Jo31 and CT60 gene polymorphisms.

European journal of endocrinology - 1 Nov 2009

Daroszewski Jacek, Pawlak Edyta, Karabon Lidia, Frydecka Irena, Jonkisz Anna, Slowik Miroslaw, Bolanowski Marek

Abstract excerpt

OBJECTIVE: Graves' disease (GD) is an autoimmune disorder with genetic and environmental background. CTLA-4 is a candidate gene for thyroid autoimmunity. Increased serum levels of soluble CTLA-4 (sCTLA-4) were found in some autoimmune diseases. AIM: The aim of the study was to evaluate the relation between sCTLA-4 level and clinical manifestation of Graves' ophthalmopathy (GO), thyroid status, and CTLA-4 gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CTLA-4 Antigen

Share to Graves Ophthalmopathy

Share to Statistics, Nonparametric

Share to Thyrotropin

Share to Thyroxine

Share to Triiodothyronine

Source

Identifiers

PMID: 19734241
DOI: 10.1530/EJE-09-0600

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Soluble CTLA-4 receptor an immunological marker of Graves' disease and severity of ophthalmopathy is associated with CTLA-4 Jo31 and CT60 gene polymorphisms.PMID 19734241Read ↗

Association of CTLA-4 +49 A/G and CT60 Gene Polymorphism with Graves' Disease.Semantic proximity Read ↗

A significant association of the CTLA4 gene variants with the risk of autoimmune Graves' disease in ethnic Kashmiri population.Semantic proximity Read ↗

CTLA4 polymorphisms and ophthalmopathy in Graves' disease patients: association study and meta-analysis.Semantic proximity Read ↗

CT60 single nucleotide polymorphisms of the cytotoxic T-lymphocyte-associated antigen-4 gene region is associated with Graves' disease in an Italian population.Semantic proximity Read ↗

Association of Cytotoxic T-Lymphocyte Antigen 4 (CTLA4) and Thyroglobulin (TG) Genetic Variants with Autoimmune Hypothyroidism.Semantic proximity Read ↗

CD28/CTLA-4/ICOS haplotypes confers susceptibility to Graves' disease and modulates clinical phenotype of disease.Semantic proximity Read ↗

The associations between the polymorphisms in the CTLA-4 gene and the risk of Graves' disease in the Chinese population.Semantic proximity Read ↗

Association of CT60 polymorphism of the CTLA4 gene with Graves' disease in Taiwanese children.Semantic proximity Read ↗

The common -318C/T polymorphism in the promoter region of CTLA4 gene is associated with reduced risk of ophthalmopathy in Chinese Graves' patients.Semantic proximity Read ↗

Meta-Analysis of CTLA-4 +49 Gene Polymorphism and Susceptibility to Graves' Disease.Semantic proximity Read ↗

Association between CTLA-4 polymorphisms and the susceptibility to systemic lupus erythematosus and Graves' disease in Thai population.Semantic proximity Read ↗

The Development of Graves' Disease and the CTLA-4 Gene on Chromosome 2q33Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.