Article

Selective epithelial expression of <i>KRAS</i> <sup>G12D</sup> mutation drives ductal pancreatic neoplasia in Oncopigs

2024-02-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Pancreatic ductal adenocarcinoma (PDAC) remains a formidable challenge in oncology, characterized by a high mortality rate, largely attributable to delayed diagnosis and the intricacies of its tumor microenvironment. Innovations in modeling pancreatic epithelial transformation provide valuable insights into the pathogenesis and potential therapeutic strategies for PDAC. <h4>...

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Literature Corpus work: a8bd2a6c-3859-5f42-87f7-71252048bb7a
DOI: 10.1101/2024.02.01.578513

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