Article

Using human genetics to understand the effect of modulating targets of antihypertensive drugs in pregnancy

2026-05-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Aims</h4> Hypertension during pregnancy is a major cause of maternal and neonatal morbidity and mortality, yet the efficacy and safety of antihypertensive treatments in this setting remain uncertain. We evaluated the effects of antihypertensive drug targets on adverse pregnancy-related outcomes using genetic variants to instrument target perturbation. <h4>Methods</h4> We per...

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Literature Corpus work: a4925cb4-759c-587c-96ef-1ac247c4ce99
DOI: 10.64898/2026.05.12.26352361

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