Article
Using human genetic variation to estimate the effect of lipoprotein(a) lowering on pregnancy outcomes
2026-05-20
Abstract excerpt
<h4>Background</h4> Lipoprotein(a) (Lp[a]) is a genetically determined causal and independent cardiovascular risk factor and Lp(a) targeted therapies are being developed. However, evidence on the safety of substantial Lp(a) lowering during pregnancy is limited. We evaluated the impact of Lp(a) lowering on adverse pregnancy and perinatal outcomes (APPOs) using human genetic evidence. <h4>Material and Method</h4>...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 4487289d-64a4-5202-8cc2-35d6982459d1
- DOI
- 10.64898/2026.05.18.26351595