Article
Maternal Hypertension Increases Risk of Preeclampsia and Low Fetal Birthweight: Genetic Evidence From a Mendelian Randomization Study.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 2022
Ardissino Maddalena, Slob Eric A W, Millar Ophelia, Reddy Rohin K, Lazzari Laura, Patel Kiran Haresh Kumar, Ryan David, Johnson Mark R, Gill Dipender, Ng Fu Siong
Abstract excerpt
BACKGROUND: Maternal cardiovascular risk factors have been associated with adverse maternal and fetal outcomes. Given the difficulty in establishing causal relationships using epidemiological data, we applied Mendelian randomization to explore the role of cardiovascular risk factors on risk of developing preeclampsia or eclampsia, and low fetal birthweight. METHODS: Uncorrelated single-nucleotide polymorphisms...
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