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Article

Antihypertensive drug targets and breast cancer risk: a two-sample Mendelian randomization study.

European journal of epidemiology - 1 May 2024

Zheng Guoqiao, Chattopadhyay Subhayan, Sundquist Jan, Sundquist Kristina, Ji Jianguang

Abstract excerpt

Findings on the correlation between the use of antihypertensive medication and the risk of breast cancer (BC) have been inconsistent. We performed a two-sample Mendelian randomization (MR) using instrumental variables to proxy changes in gene expressions of antihypertensive medication targets to interrogate this. Genetic instruments for expression of antihypertensive drug target genes were identified with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38396187
DOI: 10.1007/s10654-024-01103-x
PMCID: PMC11219410

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