Article

Genetic variants related to antihypertensive targets inform drug efficacy and side effects

2018-11-05

Abstract excerpt

<h4>Background</h4> Drug effects can be investigated through natural variation in the genes for their protein targets. We aimed to use this approach to explore the potential side effects and repurposing potential of antihypertensive drugs, which are amongst the most commonly used medications worldwide. <h4>Methods</h4> We identified genetic instruments for antihypertensive drug classes as variants in the gene fo...

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Literature Corpus work: 5cc2da9b-ac00-56f4-8808-c3992ab790fb
DOI: 10.1101/460543

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