Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Insights Into Perinatal Outcomes of Maternal Antihypertensive Therapy During Pregnancy.

JAMA network open - 1 Aug 2024

Barry Ciarrah-Jane S, Walker Venexia M, Burden Christy, Havdahl Alexandra, Davies Neil M

Abstract excerpt

Importance: Limited information exists regarding the impact of pharmacotherapy in pregnancy due to ethical concerns of unintended fetal harm. Yet, maternal prescriptive drug use for chronic conditions such as hypertension is common. Objective: To investigate potential causal relationships between perturbing maternal genetic variants influencing antihypertensive drug targets and perinatal outcomes among offspring...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antihypertensive Agents
Share to Blood Pressure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension

Share to Infant, Newborn

Share to Mendelian Randomization Analysis

Share to Norway

Share to Pregnancy

Share to Pregnancy Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 39190310
DOI: 10.1001/jamanetworkopen.2024.26234
PMCID: PMC11350473

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Insights Into Perinatal Outcomes of Maternal Antihypertensive Therapy During Pregnancy.PMID 39190310Read ↗

Using human genetics to understand the effect of modulating targets of antihypertensive drugs in pregnancySemantic proximity Read ↗

Maternal hypertensive traits and adverse outcome in pregnancy: a Mendelian randomization study.Semantic proximity Read ↗

Using human genetic variation to estimate the effect of lipoprotein(a) lowering on pregnancy outcomesSemantic proximity Read ↗

Genetic Variation in Cardiometabolic Traits and Medication Targets and the Risk of Hypertensive Disorders of PregnancySemantic proximity Read ↗

Preeclampsia, gestational hypertension, and cardiovascular disease risk: a genetic epidemiological studySemantic proximity Read ↗

Genetic Risk Factors Associated With Preeclampsia and Hypertensive Disorders of PregnancySemantic proximity Read ↗

Blood Pressure Genetic Risk and Incident Hypertension at 2 to 7 Years Post Partum.Semantic proximity Read ↗

Hypertensive disorders of pregnancy and risk of cardiovascular disease: A Mendelian Randomisation study in the UK BiobankSemantic proximity Read ↗

Associations Between Pregnancy-Related Predisposing Factors for Offspring Neurodevelopmental Conditions and Parental Genetic Liability to Attention-Deficit/Hyperactivity Disorder, Autism, and SchizophreniaSemantic proximity Read ↗

Maternal Hypertension Increases Risk of Preeclampsia and Low Fetal Birthweight: Genetic Evidence From a Mendelian Randomization Study.Semantic proximity Read ↗

Pregnancy-Associated Hypertension and Offspring Cardiometabolic HealthSemantic proximity Read ↗

Dissecting the relationship between hypertensive disorders of pregnancy and branched-chain amino acids: An integrated investigation combining Mendelian randomization, transcriptomics, and machine learning.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.