Article
Maternal hypertensive traits and adverse outcome in pregnancy: a Mendelian randomization study.
Journal of hypertension - 1 Sept 2023
Ardissino Maddalena, Reddy Rohin K, Slob Eric A W, Griffiths Jack, Girling Joanna, Ng Fu Siong
Abstract excerpt
INTRODUCTION: Hypertensive disorders of pregnancy are associated with adverse feto-maternal outcomes. Existing evidence is mostly limited to observational studies, which are liable to confounding and bias. This study investigated the causal relevance of component hypertensive indices on multiple adverse pregnancy outcomes using Mendelian randomization. METHODS: Uncorrelated ( r2 < 0.001) genome-wide significant...
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