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Article

Genome-wide assessment of <i>Mycobacterium tuberculosis</i> conditionally essential metabolic pathways

2019-01-29

Abstract excerpt

Better understanding of essential cellular functions in pathogenic bacteria is important for the development of more effective antimicrobial agents. We performed a comprehensive identification of essential genes in Mycobacterium tuberculosis , the major causative agent of tuberculosis, using a combination of transposon insertion sequencing (Tn-seq) and comparative genomic analysis. To identify conditional essenti...

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Literature Corpus work
a47faca2-7edd-5318-a6c7-b1232c8c0457
DOI
10.1101/534289
Open publication

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Genome-wide assessment of <i>Mycobacterium tuberculosis</i> conditionally essential metabolic pathwaysDOI 10.1101/534289
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