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The <i>Mycobacterium tuberculosis</i> long-chain fatty acid resistome reveals the universal stress protein TB15.3 as essential for infection

2025-04-14

Abstract excerpt

<h4>ABSTRACT</h4> The human pathogen Mycobacterium tuberculosis (Mtb) thrives in lipid-rich microenvironments. Long-chain fatty acids (LCFA) are some of the most abundant lipids encountered by Mtb during infection. Mtb has evolved to utilize LCFA as a preferred carbon source, however, LCFA are also known to be potent antimicrobials. Mtb must therefore employ mechanisms to utilize LCFA as a carbon source while av...

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Literature Corpus work
06cfb026-81b6-51de-a091-91c04b699aa2
DOI
10.1101/2025.04.14.648703
Open publication

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The <i>Mycobacterium tuberculosis</i> long-chain fatty acid resistome reveals the universal stress protein TB15.3 as essential for infectionDOI 10.1101/2025.04.14.648703
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