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Article

Transposon sequencing reveals metabolic pathways essential for Mycobacterium tuberculosis infection.

PLoS pathogens - 1 Mar 2024

Block Alisha M, Wiegert Parker C, Namugenyi Sarah B, Tischler Anna D

Abstract excerpt

New drugs are needed to shorten and simplify treatment of tuberculosis caused by Mycobacterium tuberculosis. Metabolic pathways that M. tuberculosis requires for growth or survival during infection represent potential targets for anti-tubercular drug development. Genes and metabolic pathways essential for M. tuberculosis growth in standard laboratory culture conditions have been defined by genome-wide genetic...

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Identifiers

PMID: 38498580
DOI: 10.1371/journal.ppat.1011663
PMCID: PMC10977890

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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