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Probing differences in gene essentiality between the human and animal adapted lineages of the <i>Mycobacterium tuberculosis</i> complex using TnSeq

2021-09-21

Abstract excerpt

Members of the Mycobacterium tuberculosis complex (MTBC) show distinct host adaptations, preferences and phenotypes despite being >99% identical at the nucleic acid level. Previous studies have explored gene expression changes between the members, however few studies have probed differences in gene essentiality. To better understand the functional impacts of the nucleic acid differences between Mycobacterium bovi...

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Literature Corpus work
f123064d-7db8-5689-bb96-9395d4353c83
DOI
10.1101/2021.09.21.461195
Open publication

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Probing differences in gene essentiality between the human and animal adapted lineages of the <i>Mycobacterium tuberculosis</i> complex using TnSeqDOI 10.1101/2021.09.21.461195
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