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The <i>Mycobacterium tuberculosis</i> transposon sequencing database (MtbTnDB): a large-scale guide to genetic conditional essentiality

2021-03-06

Abstract excerpt

Characterizing genetic essentiality across various conditions is fundamental for understanding gene function. Transposon sequencing (TnSeq) is a powerful technique to generate genome-wide essentiality profiles in bacteria and has been extensively applied to Mycobacterium tuberculosis (Mtb). Dozens of TnSeq screens have yielded valuable insights into the biology of Mtb in vitro, inside macrophages, and in model ho...

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Literature Corpus work
e216713c-a61c-5a17-a0a6-1c312e5cb136
DOI
10.1101/2021.03.05.434127
Open publication

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The <i>Mycobacterium tuberculosis</i> transposon sequencing database (MtbTnDB): a large-scale guide to genetic conditional essentialityDOI 10.1101/2021.03.05.434127
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