Article

Accelerometry-Derived REM Sleep Behavior Disorder Predicts Future Parkinson’s Disease in the UK Biobank

2026-07-06

Abstract excerpt

<h4>ABSTRACT</h4> Estimating Parkinson’s disease (PD) risk years before diagnosis remains an unmet need. We applied a validated machine learning classifier for REM sleep behavior disorder (RBD) detection to 7-day wrist accelerometry data in 87,975 UK Biobank participants followed for 10 years. Participants in the highest RBD risk stratum (>99 th percentile) had an approximately fivefold increased hazard of incid...

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Literature Corpus work: daa23589-c268-5856-9738-c33774c1a471
DOI: 10.64898/2026.07.02.26356952

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