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Article

Sleep/wake cycle alterations as a cause of neurodegenerative diseases: A Mendelian randomization study

24 May 2021

Abstract excerpt

Sleep and/or wake cycle alterations are common in neurodegenerative diseases (ND). Our aim was to determine whether there is a causal relationship between sleep and/or wake cycle patterns and ND (Parkinson's disease (PD) age at onset (AAO), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS)) using two-sample Mendelian Randomization (MR). We selected 12 sleep traits with available Genome-Wide...

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Identifiers

PMID: 34130902
DOI: 10.1016/j.neurobiolaging.2021.05.008

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