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Article

Relationship between sleep and progression of Parkinson’s disease – A Mendelian randomization study

2024-01-23

Abstract excerpt

<h4>Background</h4> Sleep disturbances are common in Parkinson’s disease (PD) and growing evidence suggests a bidirectional relationship between sleep disruption and neurodegeneration. <h4>Objectives</h4> To study the causal relationship between sleep and rate of PD progression using two-sample Mendelian randomisation (MR). <h4>Methods</h4> Genetic variants linked to sleep duration and insomnia were analysed withi...

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Literature Corpus work
3bc8055a-c59a-567b-a814-b8bbe083d56c
DOI
10.1101/2024.01.22.24301618
Open publication

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Relationship between sleep and progression of Parkinson’s disease – A Mendelian randomization studyDOI 10.1101/2024.01.22.24301618
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