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Article

Megabase-scale methylation phasing using nanopore long reads and NanoMethPhase.

Genome biology - 22 Feb 2021

Akbari Vahid, Garant Jean-Michel, O'Neill Kieran, Pandoh Pawan, Moore Richard, Marra Marco A, Hirst Martin, Jones Steven J M

Abstract excerpt

The ability of nanopore sequencing to simultaneously detect modified nucleotides while producing long reads makes it ideal for detecting and phasing allele-specific methylation. However, there is currently no complete software for detecting SNPs, phasing haplotypes, and mapping methylation to these from nanopore sequence data. Here, we present NanoMethPhase, a software tool to phase 5-methylcytosine from nanopore...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33618748
DOI: 10.1186/s13059-021-02283-5
PMCID: PMC7898412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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