Article

DeepMP: a deep learning tool to detect DNA base modifications on Nanopore sequencing data

2021-06-28

Abstract excerpt

<h4>Motivation</h4> DNA Methylation plays a key role in a variety of biological processes. Recently, Nanopore long-read sequencing has enabled direct detection of these modifications. As a consequence, a range of computational methods have been developed to exploit Nanopore data for methylation detection. However, current approaches rely on a human-defined threshold to detect the methylation status of a genomic p...

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Literature Corpus work: 76db5264-0473-5f36-b56c-1d3d28273e2b
DOI: 10.1101/2021.06.28.450135

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