Article
Plasma proteomic associations with genetics and health in the UK Biobank.
Nature - 1 Oct 2023
Sun Benjamin B, Chiou Joshua, Traylor Matthew, Benner Christian, Hsu Yi-Hsiang, Richardson Tom G, Surendran Praveen, Mahajan Anubha, Robins Chloe, Vasquez-Grinnell Steven G, Hou Liping, Kvikstad Erika M, Burren Oliver S, Davitte Jonathan, Ferber Kyle L, Gillies Christopher E, Hedman Åsa K, Hu Sile, Lin Tinchi, Mikkilineni Rajesh, Pendergrass Rion K, Pickering Corran, Prins Bram, Baird Denis, Chen Chia-Yen, Ward Lucas D, Deaton Aimee M, Welsh Samantha, Willis Carissa M, Lehner Nick, Arnold Matthias, Wörheide Maria A, Suhre Karsten, Kastenmüller Gabi, Sethi Anurag, Cule Madeleine, Raj Anil, Burkitt-Gray Lucy, Melamud Eugene, Black Mary Helen, Fauman Eric B, Howson Joanna M M, Kang Hyun Min, McCarthy Mark I, Nioi Paul, Petrovski Slavé, Scott Robert A, Smith Erin N, Szalma Sándor, Waterworth Dawn M, Mitnaul Lyndon J, Szustakowski Joseph D, Gibson Bradford W, Miller Melissa R, Whelan Christopher D
Abstract excerpt
The Pharma Proteomics Project is a precompetitive biopharmaceutical consortium characterizing the plasma proteomic profiles of 54,219 UK Biobank participants. Here we provide a detailed summary of this initiative, including technical and biological validations, insights into proteomic disease signatures, and prediction modelling for various demographic and health indicators. We present comprehensive protein...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.