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Article

Systematic discovery of gene-environment interactions underlying the human plasma proteome in UK Biobank

2023-10-26

Abstract excerpt

Understanding how gene-environment interactions (GEIs) influence the circulating proteome could aid in biomarker discovery and validation. The presence of GEIs can be inferred from single nucleotide polymorphisms that associate with phenotypic variability - termed variance quantitative trait loci (vQTLs). Here, vQTL association studies are performed on plasma levels of 1,468 proteins in 53,752 UK Biobank participa...

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Literature Corpus work
333790a8-90c7-52fb-ada9-a390616bedea
DOI
10.1101/2023.10.26.23297604
Open publication

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Systematic discovery of gene-environment interactions underlying the human plasma proteome in UK BiobankDOI 10.1101/2023.10.26.23297604
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