Article
Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion.
The Journal of biological chemistry - 28 Apr 2017
Horsthemke Markus, Bachg Anne C, Groll Katharina, Moyzio Sven, Müther Barbara, Hemkemeyer Sandra A, Wedlich-Söldner Roland, Sixt Michael, Tacke Sebastian, Bähler Martin, Hanley Peter J
Abstract excerpt
Macrophage filopodia, finger-like membrane protrusions, were first implicated in phagocytosis more than 100 years ago, but little is still known about the involvement of these actin-dependent structures in particle clearance. Using spinning disk confocal microscopy to image filopodial dynamics in mouse resident Lifeact-EGFP macrophages, we show that filopodia, or filopodia-like structures, support pathogen...
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