Article
Apoptotic body-inspired nanoparticles target macrophages at sites of inflammation to support an anti-inflammatory phenotype shift.
International journal of pharmaceutics - 25 Apr 2022
Kraynak Chelsea A, Huang Wenbai, Bender Elizabeth C, Wang Jie-Liang, Hanafy Mahmoud S, Cui Zhengrong, Suggs Laura J
Abstract excerpt
Chronic inflammation is a significant pathological process found in a range of disease states. Treatments to reduce inflammation in this family of diseases may improve symptoms and disease progression, but are largely limited by variable response rates, cost, and off-target effects. Macrophages are implicated in many inflammatory diseases for their critical role in the maintenance and resolution of inflammation....
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