Article

A simple and effective method to purify and activate T cells for successful generation of chimeric antigen receptor T (CAR-T) cells from patients with high monocyte count.

2022-11-11

Abstract excerpt

<title>Abstract</title> Background Chimeric antigen receptor T (CAR-T) cells are genetically modified T cells with redirected specificity and potent T-cell-mediated cytotoxicity toward malignant cells. Despite several CAR-T products being approved and commercialized in the USA, Europe, and China, CAR-T products still requires additional optimiztion to ensure reproducible and cost-effective manufacture. Here, w...

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Literature Corpus work: a3ce6b3f-9905-5c9c-adb1-685cb34aa220
DOI: 10.21203/rs.3.rs-2237534/v1

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