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Article

Large Scale In-House Point-of-Care Manufacturing of Clinical Grade Autologous Anti-CD19 CAR T Cells in Saudi Arabia

2024-06-12

Abstract excerpt

<h4>ABSTRACT</h4> Chimeric Antigen Receptor T (CAR T) cell therapy targeting the CD19 antigen represents a significant advancement in the treatment of various subtypes of CD19-expressing hematologic malignancies. Nevertheless, the current commercial CAR T manufacturing process is intricate, time-consuming, and costly, involving a supply chain that initiates at the treating center with mononuclear cell apheresis, f...

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Literature Corpus work
81ec464f-d5ab-5ba3-adc6-25404c7d4737
DOI
10.1101/2024.06.11.24308741
Open publication

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Large Scale In-House Point-of-Care Manufacturing of Clinical Grade Autologous Anti-CD19 CAR T Cells in Saudi ArabiaDOI 10.1101/2024.06.11.24308741
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