Article

Microfluidic T-Chip enables one-step clinical-scale T-cell purification from blood products for CAR T-cell manufacturing

2026-07-31

Abstract excerpt

Treatment with chimeric antigen receptor (CAR) T cells has emerged as a promising immune therapy for relapsed and refractory hematologic malignancies. The CAR T cells are manufactured in a series of steps that involve isolating T cells from the patient’s leukapheresis product, genetically modifying them to express the CAR against the target antigen, and reinfusing them into the patient. Efficient T-cell enrichment...

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Literature Corpus work: 2025881c-448d-5fec-9f5f-cb32a6b57da1
DOI: 10.64898/2026.07.30.741793

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