Article

Optimized Protocols for in Vitro T Cell-Dependent and T Cell-Independent Activation for B Cell Differentiation Studies Using Limited Cells<strong> </strong>

2021-11-22

Abstract excerpt

<h4>Background: </h4> /methods: For mechanistic studies, in vitro human B cell differentiation and generation of plasma cells are invaluable techniques. However, the heterogeneity of both T cell-dependent (TD) and T cell-independent (TI) stimuli and the disparity of culture conditions used in existing protocols makes interpretation of results challenging. The aim of the present study was to achieve the most optima...

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Literature Corpus work: 8e16438d-3c1a-5f8c-84b9-6698065f69a7
DOI: 10.20944/preprints202111.0365.v2

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