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GPCR-targeted imaging and manipulation of homeostatic microglia in living systems

2025-04-06

Abstract excerpt

Microglia, the resident innate immune cells of the brain, are known to perform key roles such as synaptic pruning, apoptotic debris removal, and pathogen defense in the central nervous system. Microglial mutations are directly linked to many neurodevelopmental (e.g., schizophrenia) and neurodegenerative (e.g., Alzheimer’s disease) disorders, indicating the diagnostic and therapeutic potential of microglia for trea...

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Literature Corpus work
a3c79cb1-d2e2-586f-b951-28ac15665eeb
DOI
10.1101/2025.04.01.646501
Open publication

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GPCR-targeted imaging and manipulation of homeostatic microglia in living systemsDOI 10.1101/2025.04.01.646501
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