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Article

Microglia remodelling and neuroinflammation parallel neuronal hyperactivation following acute organophosphate poisoning

2022-05-31

Abstract excerpt

<h4>Background: </h4> Organophosphate (OP) compounds include highly toxic chemicals widely used both as pesticides and as warfare nerve agents. Existing countermeasures are lifesaving but do not alleviate all long-term neurological sequelae, making OP poisoning a public health concern worldwide and the search for fully efficient antidotes an urgent need. OPs cause irreversible acetylcholinesterase (AChE) inhibitio...

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Literature Corpus work
30cedea1-0c93-5d7d-9743-8aa00edf2f27
DOI
10.21203/rs.3.rs-1662275/v1
Open publication

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Microglia remodelling and neuroinflammation parallel neuronal hyperactivation following acute organophosphate poisoningDOI 10.21203/rs.3.rs-1662275/v1
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