Article

Capped nascent RNA sequencing reveals novel therapy-responsive enhancers in prostate cancer

2022-04-10

Abstract excerpt

Mounting evidence suggests that enhancer RNA (eRNA) transcription start sites (TSSs) provide higher sensitivity and specificity for enhancer identification than histone modifications and chromatin accessibility. The extent to which changes in eRNA transcription correspond to changes in enhancer activity, however, remains unclear. Here, we used precision run-on and capped RNA sequencing (PRO-cap) to assess changes...

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Literature Corpus work: a3c09622-7bee-555c-9ae8-b8f9d04680ef
DOI: 10.1101/2022.04.08.487666

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