Article
Enhanced Identification of Transcriptional Enhancers Provides Mechanistic Insights into Diseases.
Trends in genetics : TIG - 1 Feb 2016
Murakawa Yasuhiro, Yoshihara Masahito, Kawaji Hideya, Nishikawa Miki, Zayed Hatem, Suzuki Harukazu, Fantom Consortium, Hayashizaki Yoshihide
Abstract excerpt
Enhancers are distal cis-regulatory DNA elements that increase the expression of target genes. Various experimental and computational approaches including chromatin signature profiling have been developed to predict enhancers on a genome-wide scale, although each method has its advantages and disadvantages. Here we overview an emerging method to identify transcribed enhancers at exceedingly high nucleotide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
