Article

<i>Drosophila scribble</i> mutant tumors undergo a transition from a growth arrest state to a proliferative state over time

2018-10-23

Abstract excerpt

<h4>Summary</h4> The Drosophila neoplastic tumor suppressor gene (nTSG) mutant tumors have successfully modeled many aspects of human tumor progression. However, the fly nTSG mutant tumors progress rapidly over days. This is in contrast with most human tumors which develop slowly, harbor heterogeneous cell populations for selection and undergo an evolution-like process. Whether the fast-growing fly nTSG mutant t...

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Literature Corpus work: a3bd3b18-e65d-53bb-8373-d085e774f732
DOI: 10.1101/450486

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