Article

Predicting regional somatic mutation rates using DNA motifs

2022-08-05

Abstract excerpt

How the locus-specificity of epigenetic modifications is regulated remains an unanswered question. A contributing mechanism is that epigenetic enzymes are recruited to specific loci by DNA binding factors recognizing particular sequence motifs (referred to as epi-motifs). Using these motifs to predict biological outputs depending on local epigenetic state such as somatic mutation rates would confirm their function...

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Literature Corpus work: a3acd614-7b33-5bad-8a53-0ec648aee72c
DOI: 10.1101/2022.08.04.502732

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