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Article

Predicting regional somatic mutation rates using DNA motifs.

PLoS computational biology - 1 Oct 2023

Liu Cong, Wang Zengmiao, Wang Jun, Liu Chengyu, Wang Mengchi, Ngo Vu, Wang Wei

Abstract excerpt

How the locus-specificity of epigenetic modifications is regulated remains an unanswered question. A contributing mechanism is that epigenetic enzymes are recruited to specific loci by DNA binding factors recognizing particular sequence motifs (referred to as epi-motifs). Using these motifs to predict biological outputs depending on local epigenetic state such as somatic mutation rates would confirm their...

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Identifiers

PMID: 37782656
DOI: 10.1371/journal.pcbi.1011536
PMCID: PMC10569533

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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