Article

In-silico analysis of BCL2 gene using multiple bioinformatics tools to identify the most lethal mutations that are crucial for its structural and functional integrity

2021-08-23

Abstract excerpt

BCL2 was the first ever known gene for anti-apoptotic activity, that encodes for essential proteins of the external mitochondrial membrane. Regarding tumorigenesis, deregulated BCL2 expression and related proteins have been recognized as characteristic of several human cancers and there is concrete evidence that the deregulated expression of BCL2 like proteins plays a vital role in tumor development, persistence a...

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Literature Corpus work: a3a9c1ce-7875-553b-ab71-e0c0f774c48e
DOI: 10.21203/rs.3.rs-310735/v4

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