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Article

The deadly landscape of pro‐apoptotic BCL ‐2 proteins in the outer mitochondrial membrane

14 Dec 2015

Abstract excerpt

Apoptosis is a biological process that removes damaged, excess or infected cells through a genetically controlled mechanism. This process plays a crucial role in organismal development, immunity and tissue homeostasis, and alterations in apoptosis contribute to human diseases including cancer and auto-immunity. In the past two decades, significant efforts have focused on understanding the function of the BCL-2...

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PMID: 26662859
DOI: 10.1111/febs.13624

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